影响力医生

姓      名  : 孙国平

性      别  :

专      业  : 肿瘤

职      称  : 主任医师

医      院  : 安徽医科大学第一附属医院

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详细信息: 肿瘤内科,副院长博士、二级教授,一级主任医师,博士生导师,安徽省江淮名医,安徽省教学名师,享受安徽省政府津贴。 现任安徽医科大学第一附属医院副院长、高新医院院长,安徽省肿瘤防治所副所长(兼),安徽医科大学科肿瘤研究所所长。兼任兼任中国药理学会临床药理专业委员会常委、中国医药生物技术协会精准医疗分会常委、世界华人肿瘤医师协会常委、中国抗癌协会抗癌药物专业委员会委员、安徽省医师协会肿瘤医师分会主任委员、安徽省医学会肿瘤学分会副主任委员(候任主委)、安徽省抗癌协会副理事长、安徽省肿瘤治疗中心副主任,安徽省生物医药技术协会副理事长,安徽省环境致突变研究协会副理事长,安徽省肿瘤内科学会常委,安徽省生物工程学会常委、安徽省药学会临床药理专业委员会常委,安徽省科学家企业家协会理事等学会兼职。 主持国家自然科学基金项目5项及10余项省级科研项目,发表论文二百余篇,其中SCI论文79篇,总影响因子408,篇均影响因子5.2,其中JCR Q1区论文34篇,占比43%。Web of Science核心合集总被引次数1674次,他引1629次,H指数21,其中多篇论文多次入选高被引论文和热点论文。获得国家专利一项,安徽省科技进步奖一项,安徽省教学成果二等奖2项。担任多部国家规划教材编写,任主编和副主编。 主持的科研项目 1、内质网应激相关超级增强子对肝癌细胞自噬的调控及其对化疗药物敏感性的影响,NO.81872047国家自然科学基金;2019-2022 ;57万 ; 2.内质网应激诱导的exosomes释放对肿瘤微环境的调控及其在肝癌免疫逃逸中的作用 NO.81572430国家自然科学基金;2016-2019 ;68万 ; 3. “肝癌细胞内质网应激耐受特异miRNAs鉴定及其对化疗敏感性影响的机制” NO:81272739国家自然科学基金;2013-2016 ;70万 ; 4.“肝癌细胞逃避内质网应激介导的凋亡的分子机制及丹皮酚的干预作用”, NO:81071986国家自然科学基金;2011-2013;36万; 5. “COX-2 通过G 蛋白-AC-cAMP-PKA 途径调控肝癌细胞IAPs 表达及丹皮酚的作用”, NO:30772537国家自然科学基金;2008-2010;29万; 6. “COX-2在肝癌细胞抵抗内质网应激性凋亡中的作用及丹皮酚的干预作用” NO:20113420110002教育部高等学校博士学科点专项科研基;2011-2013;12万; 7.“循环miRNA作为肿瘤标志物在消化道肿瘤诊断中的临床应用研究 ”NO.12010402122 安徽省科技攻关项目 20万 ; 著作 1.研究生国家级规划教材《临床药物治疗学》(教育部、国家卫生健康委员会第三轮普通高等教育医学专业) 人民卫生出版社,主编,2019年 2.《药理学》,第三版(国家卫生计生委八年制规划教材),人民卫生出版社,副主编,2014年 3.《临床药物治疗学各论》,第一版,人民卫生出版社,副主编,2014年 4.《肿瘤学》,第二版(国家卫生计生委八年制规划教材),人民卫生出版社,编委,2014年 5.《临床医学概论》, 人民卫生出版社,编委,2011年 6.《临床药物肿瘤学图表解》,第一版,人民卫生出版社,编委,2008年 7.《肿瘤学概论》,第一版,人民军医出版社,编委,2006年 8.《临床药物治疗学》,第二版(卫生部规划本科教材),人民卫生出版社,编委,2007年 奖励 “COX-2抑制剂靶向治疗消化系肿瘤的关键技术与应用”2014年安徽省科技进步二等奖,孙国平、沈玉先、范璐璐、仲飞、彭万仁、马泰、王华, 专利: “丹皮酚在制备抗食管癌药物中的应用”国家知识产权局,孙国平,桂双英,王华(专利号:ZL200610096653.X) 发表SCI论文( 79篇) 1. Liu J, Fan L, Yu H, Zhang J, He Y, Feng D, Wang F, Li X, Liu Q, Li Y, Guo Z, Gao B, Wei W, Wang H, Sun G(Corresponding author).Endoplasmic Reticulum Stress Promotes Liver Cancer Cells to Release Exosomal miR-23a-3p and Up-regulate PD-L1 Expression in Macrophages.Hepatology. 2019 Mar 10. doi: 10.1002/hep.3060 2. Xu J, Liu P, Da J, Hao J, Peng W, Sun G(Corresponding author).Prognostic value of Ki-67 in stage I non-small-cell lung cancer: A meta-analysis involving 1931 patients.Pathol Res Pract. 2019 Mar 4. pii: S0344-0338(18)31789-8. 3. Pan Z, Chen M, Hu X, Wang H, Yang J, Zhang C, Pan F, Sun G(Corresponding author).Associations between VDR gene polymorphisms and colorectal cancer susceptibility: an updated meta-analysis based on 39 case-control studies.Oncotarget. 2018 Jan 4;9(16):13068-13076. 4. Wang H, Zhang M, Sun G(Corresponding author).Long non-coding RNA NEAT1 regulates the proliferation, migration and invasion of gastric cancer cells via targeting miR-335-5p/ROCK1 axis.Pharmazie. 2018 Mar 5;73(3):150-155. 5. Sun G(First author),Li D,Ning Z,et al.A real world study of apatinib treatment in gastric cancer: Current status and clinical benefit.Annals of Oncology 2018;29:230-230 6. Luo JL,Cao CY ,Xu HQ ,Sun GP (Corresponding author), Liang GL,Mei B,He YH,Xue YY ,Wang H .Synthesis and Imaging of an Apoptotic Probe (99)mTc-DTPA-CBT-DEVD with Caspase-3 Controlled Self-Assembly of Nanoparticles.JOURNAL OF BIOMATERIALS AND TISSUE ENGINEERING.2018;8(10): 1410-1419 7. Li YH, Li XF, Liu JT, Wang H, Fan LL, Li J, Sun GP(Corresponding author).PKM2, a potential target for regulating cancer.Gene. 2018 Aug 20;668:48-53. 8. Wang GH , Wu PF, Zhang LH , Fang P , Chen Y , Zuo G , Wu YQ , Wang SH , Sun GP(Corresponding author) . Use of erlotinib and thalidomide in advanced NSCLC patients with acquired resistance to erlotinib: A pilot study.Pathol Res Pract. 2018 Feb;214(2):263-267. 9. Wang Q, Lu D, Fan L, Li Y, Liu Y, Yu H1, Wang H, Liu J, Sun G(Corresponding author).COX-2 induces apoptosis-resistance in hepatocellular carcinoma cells via the HIF-1α/PKM2 pathway.Int J Mol Med. 2019 Jan;43(1):475-488. 10. Jiang WJ, Feng RX, Liu JT, Fan LL, Wang H, Sun GP(Corresponding author).RICTOR expression in esophageal squamous cell carcinoma and its clinical significance.Med Oncol. 2017 Mar;34(3):32. 11. Hao Wang, Ya-Nan Zeng, Ming-Xia Zhang, Gen Li, Hui-Ying Cheng,Geng-Sheng Shi,Guo-Ping Sun(Corresponding author),Protective role of enteric-coated HuDi capsules against radiation-induced intestinal injury in mice.Int J Clin Exp Med2017;10(11):15196-15204. 12. Cheng L, Liu J, Liu Q, Liu Y, Fan L, Wang F, Yu H, Li Y, Bu L, Li X, Wei W, Wang H, Sun G(Corresponding author).Exosomes from Melatonin Treated Hepatocellularcarcinoma Cells Alter the Immunosupression Status through STAT3 Pathway in Macrophages.Int J Biol Sci. 2017 May 16;13(6):723-734. 13. Wang F, Liu J, Zou Y, Jiao Y, Huang Y, Fan L, Li X, Yu H, He C, Wei W, Wang H, Sun G(Corresponding author).MicroRNA-143-3p, up-regulated in H. pylori-positive gastric cancer, suppresses tumor growth, migration and invasion by directly targeting AKT2.Oncotarget. 2017 Apr 25;8(17):28711-28724. 14. Xu J, Huang L, Sun GP.(Corresponding author)Urinary 6-sulfatoxymelatonin level and breast cancer risk: systematic review and meta-analysis.Sci Rep. 2017 Jul 13;7(1):5353. 15. Zhu YZ,Sun G.(Corresponding author)Serum expression and significance of MicroRNA-30d-5p in esophageal squamous cell carcinoma.Int J Clin Exp Pathol.2017,10(8):8677-8685. 16. Yu Liu, Jiatao Liu, Liang Cheng, Lulu Fan,Fang Wang, Hanqing Yu,Qingqing Liu,Yuhuan Li, Lijia Bu,Xiaoqiu Li,Wei Wei,Hua Wang,Guoping Sun(Corresponding author),Melatonin increases the anti-tumor effects of sorafenib on human hepatoma cell lines via down-regulating autophagy.Int J Clin Exp Med 2017;10(9):14109-14120 17. Liu XC ,Zheng WQ,Zhang XD ,Dong MM,Sun GP(Corresponding author) ,The diagnostic and prognostic value of serum miR-206 in colorectal cancer.INTERNATIONAL JOURNAL OF CLINICAL AND EXPERIMENTAL PATHOLOGY .2017;10(7):7528-7533. 18. Chen F, Sun G(Corresponding author), Peng J.RNAi-mediated HOXD3 knockdown inhibits growth in human RKO cells.Oncol Rep. 2016 ;36(4):1793-8. 19. Peng D, Fu L, Sun G(Corresponding author).Expression analysis of the TGF-β/SMAD target genes in adenocarcinoma of esophagogastric junction.Open Med (Wars). 2016 May 16;11(1):83-86. 20. Li H , Juan L , Xia L , Wang Y, Bao Y , Sun G (Corresponding author). Thioridazine Sensitizes Esophageal Carcinoma Cell Lines to Radiotherapy-Induced Apoptosis In Vitro and In Vivo.Med Sci Monit. 2016 Jul 25;22:2624-34 21. Gao ZY, Liu Z, Bi MH, Zhang JJ, Han ZQ, Han X, Wang HY, Sun GP(Corresponding author), Liu H.Metformin induces apoptosis via a mitochondria-mediated pathway in human breast cancer cells in vitro.Exp Ther Med. 2016 May;11(5):1700-1706 22. Bu LJ, Yu HQ, Fan LL, Li XQ, Wang F, Liu JT, Zhong F, Zhang CJ, Wei W, Wang H, Sun GP(Corresponding author).Melatonin, a novel selective ATF-6 inhibitor, induces human hepatoma cell apoptosis through COX-2 downregulation.World J Gastroenterol. 2017 Feb 14;23(6):986-998. 23. Du YY, Zhang QJ, Sun GP(Corresponding author).Expression and Clinical Significance of Cytokeratin-19 and Thymidine Kinase-1 in Advanced Gastrointestinal Cancer.Chin Med J (Engl). 2016 20th Sep;129(18):2168-72. 24. Li XQ, Liu JT, Fan LL, Liu Y, Cheng L, Wang F, Yu HQ, Gao J, Wei W, Wang H, Sun GP(Corresponding author).Exosomes derived from gefitinib-treated EGFR-mutant lung cancer cells alter cisplatin sensitivity via up-regulating autophagy.Oncotarget. 2016 Apr 26; 7(17): 24585–24595. 25. Ning J,Hu LX,Zhang QJ, Jiao Y, Li M,Gu KS,Sun G.(Corresponding author).Psoriasis aggravation due to capecitabine in a colon cancer patient: a case report and literature review. INTERNATIONAL JOURNAL OF CLINICAL AND EXPERIMENTAL MEDICINE .2016;9(8):16399-16402. 26. Huang Y, Liu J, Fan L, Wang F, Yu H, Wei W, Sun G(Corresponding author).miR-663 overexpression induced by endoplasmic reticulum stress modulates hepatocellular carcinoma cell apoptosis via transforming growth factor beta 1. Onco Targets Ther. 2016 Mar 17;9:1623-33. 27. Liu J, Fan L, Wang H, Sun G(Corresponding author).Autophagy, a double-edged sword in anti-angiogenesis therapy. Med Oncol. 2016;33(1):10 28. Liu JT, Li WC, Gao S, Wang F, Li XQ, Yu HQ, Fan LL, Wei W, Wang H, Sun GP(Corresponding author)..Autophagy Inhibition Overcomes the Antagonistic Effect Between Gefitinib and Cisplatin in Epidermal Growth Factor Receptor Mutant Non-Small-Cell Lung Cancer Cells. Clin Lung Cancer. 2015. pii: S1525-7304(15)00081-9. 29. Lv Y, Wang F, Qian W, Sun G(Corresponding author). Treatment of a recurrent pulmonary artery leiomyosarcoma with a combination of surgery, chemotherapy, and radiotherapy: A case report and literature review. Oncol Lett. 2015;9(4):1545-1548. 30. Wu QB, Sun GP(Corresponding author). Expression of COX-2 and HER-2 in colorectal cancer and their correlation.World J Gastroenterol. 2015;21(20):6206-14. 31. Wang H , Fang J, Xu J, Wang F, Sun B, He S, Sun G(Corresponding author), Liu H. A hanging plasmonic droplet: three-dimensional SERS hotspots for a highly sensitive multiplex detection of amino acids.Analyst. 2015 May 7;140(9):2973-8. 32. Wang F, Sun G(Corresponding author). Methylenetetrahydrofolate reductase gene polymorphisms contribute to acute myeloid leukemia and chronic myeloid leukemia susceptibilities: appraisal of a recent meta-analysis. Cancer Epidemiol. 2014;38(6):773-774. 33. Zhang CJ, Sun GP(Corresponding author), Liu H, Peng WR, Xiong FX, Pan YY, Da J.Primary clear cell adenocarcinoma of the peritoneum presents as Sister Mary Joseph's nodule: a case report and literature review.Eur J Gynaecol Oncol.2014;35:745-748 34. Wang J, Liu S, Sun GP(Corresponding author), Wang F, Zou YF, Jiao Y, Ning J, Xu J.Prognostic significance of microRNA-221/222 expression in cancers: evidence from 1,204 subjects. Int J Biol Markers. 2014;29(2):e129-141. 35. Tian Y, Li X, Li H, Lu Q, Sun G(Corresponding author), Chen H. Astragalus mongholicus regulate the Toll-like-receptor 4 meditated signal transduction of dendritic cells to restrain stomach cancer cells.Afr J Tradit Complement Altern Med. 2014;11(3):92-96. 36. Lv Y, Wang F, Yang L, Sun G(Corresponding author).Intensity-modulated whole pelvic radiotherapy provides effective dosimetric outcomes for cervical cancer treatment with lower toxicities.Cancer Radiother. 2014;18(8):745-752. 37. Peng D, Zhang H, Sun G(Corresponding author).The relationship between P16 gene promoter methylation and gastric cancer: a meta-analysis based on Chinese patients.J Cancer Res Ther. 2014 Dec;10 Suppl:292-5 38. Ye X, Feng G, Jiao N, Pu C, Zhao G, Sun G(Corresponding author)Methylation of DLEC1 promoter is a predictor for recurrence in Chinese patients with gastric cancer.Dis Markers. 2014;2014:804023. 39. Wang F, Sun GP(Corresponding author), Zou YF, Zhong F, Ma T, Li XQ, Wu D.Helicobacter pylori infection predicts favorable outcome in patients with gastric cancer. Curr Oncol. 2013;20(5):e388-395. 40. Fan L, Sun G(Corresponding author), Ma T, Zhong F, Lei Y, Li X, Wei W.Melatonin reverses tunicamycin-induced endoplasmic reticulum stress in human hepatocellular carcinoma cells and improves cytotoxic response to doxorubicin by increasing CHOP and decreasing Survivin.J Pineal Res. 2013 ;55(2):184-194. 41. .Fan L, Sun G(Corresponding author), Ma T, Zhong F, Wei W.Melatonin overcomes apoptosis resistance in human hepatocellular carcinoma by targeting Survivin and XIAP.J Pineal Res. 2013;55(2):174-183 42. Fan L, Song B, Sun G(Corresponding author), Ma T, Zhong F, Wei W.Endoplasmic reticulum stress-induced resistance to Doxorubicin is reversed by paeonol treatment in human hepatocellular carcinoma cells.PLoS One. 2013;8(5): e62627. 43. Lei Y, Li HX, Jin WS, Peng WR, Zhang CJ, Bu LJ, Du YY, Ma T, Sun GP(Corresponding author).The radiosensitizing effect of Paeonol on lung adenocarcinoma by augmentation of radiation-induced apoptosis and inhibition of the PI3K/Akt pathway.Int J Radiat Biol. 2013;89(12):1079-1086. 44. Wang F, Sun G(Corresponding author), Zou Y, Zhong F, Ma T, Li X.Protective Role of Helicobacter pylori Infection in Prognosis of Gastric Cancer: Evidence from 2454 Patients with Gastric Cancer.PLoS One. 2013 May 7;8(5):e62440. 45. Ma T, Li YY, Zhu J, Fan LL, Du WD, Wu CH, Sun GP(Corresponding author), Li JB.Enhanced autophagic flux by endoplasmic reticulum stress in human hepatocellular carcinoma cells contributes to the maintenance of cell viability.Oncol Rep. 2013;30(1):433-440. 46. Xu H, Sun G(Corresponding author), Wang H, Yue Q, Tang H, Wu Q.Dynamic observation of the radiosensitive effect of irisquinone on rabbit VX2 lung transplant tumors by using fluorine-18-deoxyglucose positron emission tomography/computed tomography. Nucl Med Commun. 2013;34(3):22022-8. 47. Zha L, Fan L, Sun G(Co-corresponding author), Wang H, Ma T, Zhong F, Wei W.Melatonin sensitizes human hepatoma cells to endoplasmic reticulum stress-induced apoptosis. J Pineal Res. 2012;52(3):322-331. 48. Wang F, Sun GP(Corresponding author), Zou YF, Hao JQ, Zhong F, Ren WJ.MicroRNAs as promising biomarkers for gastric cancer.Cancer Biomark. 2013;11(6):259-267 49. Wang F, Sun GP(Corresponding author), Zou YF.Meat consumption and risk of lung cancer: evidence from observational studies.Ann Oncol. 2013;24(1):266-267 50. Wang F, Sun GP(Corresponding author), Zou YF, Fan LL, Song B.Quantitative assessment of the association between miR-196a2 rs11614913 polymorphism and gastrointestinal cancer risk.Mol Biol Rep. 2013;40(1):109-116. 51. Ma T,Sun GP,Li JB.Methods for Autophagy Detection. PROGRESS IN BIOCHEMISTRY AND BIOPHYSICS. 2012;39(3):204-209. 52. Wang F, Sun G(Corresponding author), Zou Y, Li Y, Hao L, Pan F.Association of microRNA-499 rs3746444 Polymorphism with Cancer Risk: Evidence from 7188 Cases and 8548 Controls. PLoS One. 2012;7(9):e45042. 53. Wang F, Sun G(Corresponding author), Zou Y.Associations between interleukin-6 gene -174 C/G and -572 C/G polymorphisms and risk of gastric cancer.J Surg Oncol. J Surg Oncol. 2013;107(7):789. (IF:2.644/2012) 54. Wang F, Sun G(Corresponding author), Zou Y, Fan L, Song B.Lack of association of miR-146a rs2910164 polymorphism with gastrointestinal cancers: evidence from 10206 subjects.PLoS One. 2012;7(6):e39623 55. Wang F, Sun G(Corresponding author), Zou Y.Association of interleukin-10- 1082 promoter polymorphism with gastric cancer: appraisal of a recent meta-analysis.DNA Cell Biol. 2012;31(5):646-7; author reply 648-650 56. Wang F, Sun GP(Corresponding author), Zou YF, Wu Q, Wu HY, Wu JF, Zhou JD, Chen K, Zhang XS.Expression of COX-2 and Bcl-2 in primary fallopian tube carcinoma: correlations with clinicopathologic features. Folia Histochem Cytobiol. 2011;49(3):389-397 57. Antitumor effect of tumor necrosis factor-related apoptosis inducing ligand combined with mevastatin on a human glioma cell line SWO-38.NEURAL REGENERATION RESEARCH.2010;5(5) 396-400. 58. Fan LL, Sun GP(Corresponding author), Wei W, Wang ZG, Ge L, Fu WZ, Wang H.Melatonin and doxorubicin synergistically induce cell apoptosis in human hepatoma cell lines.World J Gastroenterol. 2010;16(12):1473-1481. 59. Li N, Fan LL, Sun GP(Corresponding author), Wan XA, Wang ZG, Wu Q, Wang H.Paeonol inhibits tumor growth in gastric cancer in vitro and in vivo.World J Gastroenterol. 2010;16(35):4483-4490. 60. Sun GP(First author), Wang H, Xu SP, Shen YX, Wu Q, Chen ZD, Wei W.Anti-tumor effects of paeonol in a HepA-hepatoma bearing mouse model via induction of tumor cell apoptosis and stimulation of IL-2 and TNF-alpha production. Eur J Pharmacol. 2008;584(2-3):246-252. 61. Wan XA, Sun GP(Corresponding author), Wang H, Xu SP, Wang ZG, Liu SH.Synergistic effect of paeonol and cisplatin on oesophageal cancer cell lines.Dig Liver Dis. 2008;40(7):531-9. 62. Sun GP(First author), Wan X, Xu SP, Wang H, Liu SH, WangZG. Antiproliferation and apoptosis induction of paeonol in human esophageal cancer cell lines. Dis Esophagus. 2008;21(8):723-729. 63. Xu SP, Sun GP(Corresponding author), Shen YX, Peng WR, Wang H, Wei W.Synergistic effect of combining paeonol and cisplatin on apoptotic induction of human hepatoma cell lines.Acta Pharmacol Sin. 2007;28(6):869-878. 64. Xu SP, Sun GP(Corresponding author), Shen YX, Wei W, Peng WR, Wang H.Antiproliferation and apoptosis induction of paeonol in HepG2 cells.World J Gastroenterol. 2007 14;13(2):250-256. 65. Liu X, Qin S, Wang Z, Xu J, Xiong J, Bai Y, Wang Z, Yang Y, Sun G, Wang L, Zheng L, Xu N, Cheng Y, Guo W, Yu H, Liu T, Lagiou P, Li J.early presence of anti-angiogenesis-related adverse events as a potential biomarker of antitumor efficacy in metastatic gastric cancer patients treated with apatinib: a cohort study..J Hematol Oncol. 2017 Sep 5;10(1):153 66. Wang FH, Wang Y, Sun GP, Chen JH, Lin YC, Liu W, Zheng RS, Chen J, Zhang HL, Lan HT, Qi J, Liu YQ, Deng YM, Zhao H, Xiong JP, Xu Q, Jiang WQ, Li YH. Efficacy and safety of recombinant human lymphotoxin-α derivative with cisplatin and fluorouracil in patients with metastatic esophageal squamous cell carcinoma: A randomized, multicenter, open-label, controlled, phase 2b trial.Cancer. 2017 Oct 15;123(20):3986-3994. 67.Li J, Qin S, Xu J, Xiong J, Wu C, Bai Y, Liu W, Tong J, Liu Y, Xu R, Wang Z, Wang Q, Ouyang X, Yang Y, Ba Y, Liang J, Lin X, Luo D, Zheng R, Wang X, Sun G, Wang L, Zheng L, Guo H, Wu J, Xu N, Yang J, Zhang H, Cheng Y, Wang N, Chen L, Fan Z, Sun P, Yu H.Randomized, Double-Blind, Placebo-Controlled Phase III Trial of Apatinib in Patients With Chemotherapy-Refractory Advanced or Metastatic Adenocarcinoma of the Stomach or Gastroesophageal Junction.J Clin Oncol. 2016 May 1;34(13):1448-54. 68.Li YH, Qiu MZ, Xu JM, Sun GP, Lu HS, Liu YP, Zhong MZ, Zhang HL, Yu SY, Li W, Hu XH, Wang JJ, Cheng Y, Zhou JT, Guo ZQ, Guan ZG, Xu RH.S-1 plus cisplatin versus fluorouracil plus cisplatin in advanced gastric or gastro-esophageal junction adenocarcinoma patients: a pilot study.Oncotarget. 2015 Oct 27;6(33):35107-15. 69.Satoh T, Xu RH, Chung HC, Sun GP, Doi T, Xu JM, Tsuji A, Omuro Y, Li J, Wang JW, Miwa H, Qin SK, Chung IJ, Yeh KH, Feng JF, Mukaiyama A, Kobayashi M, Ohtsu A, Bang YJ. Lapatinib plus paclitaxel versus paclitaxel alone in the second-line treatment of HER2-amplified advanced gastric cancer in Asian populations: TyTAN--a randomized, phase III study.J Clin Oncol. 2014 Jul 1;32(19):2039-49. 67. Li J, Qin S, Xu J, Guo W, Xiong J, Bai Y, Sun G, Yang Y, Wang L, Xu N, Cheng Y, Wang Z, Zheng L, Tao M, Zhu X, Ji D, Liu X, Yu H. Apatinib for chemotherapy-refractory advanced metastatic gastric cancer: results from a randomized, placebo-controlled, parallel-arm, phase II trial.J Clin Oncol. 2013 Sep 10;31(26):3219-25. 68. Wang F, Zou YF, Sun GP.Association between functional IRF7 variant and systemic lupus erythematosus may need more critical examination: comment on the article by Fu et al.Arthritis Rheum. 2011 Oct;63(10):3177-8; author reply 3178-9. 72.Wang F, Zou YF, Sun GP.XPC gene polymorphisms and breast cancer susceptibility: appraisal of a recent meta-analysis.Breast Cancer Res Treat. 2011 Aug;129(1):277-9. 69. Wang F, Zou YF, Sun GP, Su H, Huang F. Association of CYP1B1 gene polymorphisms with susceptibility to endometrial cancer: a meta-analysis.Eur J Cancer Prev. 2011 Mar;20(2):112-20 70. Qin T, Liu H, Song Q, Song G, Wang HZ, Pan YY, Xiong FX, Gu KS, Sun GP, Chen ZD. The screening of volatile markers for hepatocellular carcinoma.Cancer Epidemiol Biomarkers Prev. 2010 Sep;19(9):2247-53. 71. Song G, Qin T, Liu H, Xu GB, Pan YY, Xiong FX, Gu KS, Sun GP, Chen ZD.Quantitative breath analysis of volatile organic compounds of lung cancer patients.Lung Cancer. 2010 Feb;67(2):227-31. 72. Wu H, Chen Z, Sun G, Gu K, Pan Y, Hao J, Du Y, Ning J. Intravenous flurbiprofen axetil can increase analgesic effect in refractory cancer pain.J Exp Clin Cancer Res. 2009 Mar 7;28:33. 73. Wang F ,Sun GP, Zou YF.Fulvestrant and male breast cancer: a case series.ANNALS OF ONCOLOGY 2013;24: 265-266 74. Wu H, Zhao C, Gu K, Jiao Y, Hao J, Sun G. Thalidomide plus chemotherapy exhibit enhanced efficacy in the clinical treatment of T-cell non-Hodgkin's lymphoma: A prospective study of 46 cases.Mol Clin Oncol. 2014 Sep;2(5):695-700 75. Chen F, Cui M, Fu J, Sheng G, Sun G, Xu M.Biodegradation of quinoline by freely suspended and immobilized cells of Comamonas sp strain Q10 .J Gen Appl Microbiol. 2003 Apr;49(2):123-8.

医师特长: 安徽省肿瘤防治所副所长(兼),安徽医科大学科肿瘤研究所所长。兼任兼任中国药理学会临床药理专业委员会常委、中国医药生物技术协会精准医疗分会常委、世界华人肿瘤医师协会常委、中国抗癌协会抗癌药物专业委员会委员、安徽省医师协会肿瘤医师分会主任委员、安徽省医学会肿瘤学分会副主任委员(候任主委)、安徽省抗癌协会副理事长、安徽省肿瘤治疗中心副主任,安徽省生物医药技术协会副理事长,安徽省环境致突变研究协会副理事长,安徽省肿瘤内科学会常委,安徽省生物工程学会常委、安徽省药学会临床药理专业委员会常委,安徽省科学家企业家协会理事等

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